Fresh data on Cardiovascular Research are presented in the report "IRAG and novel PKG targeting in the cardiovascular system." According to the authors of a study from Regensburg, Germany, "Signaling by nitric oxide (NO) determines several cardiovascular functions including blood pressure regulation, cardiac and smooth muscle hypertrophy, and platelet function. NO stimulates the synthesis of cGMP by soluble guanylyl cyclases and thereby activates cGMP-dependent protein kinases (PKGs), mediating most of the cGMP functions."
"Hence, an elucidation of the PKG signaling cascade is essential for the understanding of the (patho)physiological aspects of NO. Several PKG signaling …
No comments:
Post a Comment